Congenital pulmonary airway malformations (CPAM)

Congenital pulmonary airway malformations (CPAM)

Dr. Abdolohamid jafari nodushan,MD Assistant professor, pediatric pulmonologist,Department of pediatrics, Shahid Sadoughi University of medical science, yazd,iran


ongenital pulmonary airway malformations (CPAM) are multicystic masses of segmental lung tissue with abnormal bronchial proliferation. CPAMs are considered part of the spectrum of bronchopulmonary foregut malformations.

Congenital pulmonary airway malformation (CPAM), previously known as congenital cystic adenomatoid malformation (CCAM), is a developmental anomaly of the respiratory tract.

CPAMs are categorized as types 0 through 4, which are defined pathologically and have different clinical presentations and prognoses.

•Type 4 CPAMs comprise 5 to 10 percent of all CPAMs. Many of these lesions are cystic forms of pleuropulmonary blastoma (PPB), so identification and resection of these lesions is essential. Important clues that suggest this type of CPAM are presentation with pneumothorax, the presence of bilateral or multifocal lung cysts, or a family history of lung cysts or PPB-associated conditions .

Differential diagnosis

General imaging differential considerations include: